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DECA UPDATES

By: Dane Fletcher
It is estimated that there are over 100 anabolic steroids, comprised of old, new, designer, legitimate, foreign, domestic and everything in between. But among this diverse pack of AS, Nandrolone (Deca-Durabolin® brand name) is still as widely used today as ever before. It is the undisputed granddaddy of all steroids, and is used by pro bodybuilders, powerlifters, Olympic competitors (don't tell the IOC) and pro athletes around the world.

Unlike its testosterone counterparts, Deca is actually a confirmed progestin. In fact, at the site of the receptor, it actually binds better than testosterone. This is crucial to know when putting together a program of chemical enhancement, because it can be used strategically within a cycle or a specified period of time to interact positively with anabolic steroids.

1978 PDR Description:
Deca-Durabolin is nandrolone decanoate, a long-acting anabolic agent, dissolved in sesame oil for intramuscular injection. Chemically it is 19 nor-A4-androstene-17 beta-ol-3-one-decanoate.
Action: Anabolic steroids are synthetic derivatives of testosterone. The action of Deca-Durabolin (nandrolone decanoate injection N.F.) is primarily anabolic (protein sparing). It promotes body tissue-building processes and reverses catabolic or tissue depleting processes. Nitrogen balance is improved with anabolic agents but only when there is sufficient intake of calories and protein. The deletion of the CH3 group from the C-19-position has resulted in reduction of its androgenic properties and retention and enhancement of its anabolic, tissue-building properties. Thus it is possible to employ doses that provide significant anabolic effects without undesired androgenic effects. Complete dissociation of anabolic and androgenic effects has not been achieved. The actions of anabolic steroids are therefore similar to those of male sex hormones with the possibility of causing serious disturbances of growth and sexual development if given to young children-Anabolic steroids suppress the gonadotropic functions of the pituitary and may exert a direct effect upon the testis.
Indications: Based on a review of this drug by the National Academy of Sciences, National Research Council and/or other information, FDA has classified the indication(s) as follows:
Probably Effective: As adjunctive therapy in senile and post-menopausal osteoporosis. Anabolic steroids are without value as primary therapy but may be of value as adjunctive therapy. Equal or greater consideration should be given to diet, calcium balance, physiotherapy and good general health-promoting measures. In pituitary dwarfism anabolic agents may be used with care until growth hormone is more available.
Possibly Effective: In the treatment of those conditions in which a potent tissue-building or protein-sparing action is desired (eg. pre and post surgical care, burns), in the control of metastatic breast cancer and as adjuvant therapy of certain types of refractory anemia. Final classification of the less than effective indications require further investigation.
Contraindications:
1. Male patients with carcinoma of the prostate or breast.
2. Carcinoma of the breast in some females.
3. Pregnancy, because of masculinization of the fetus.
4. Nephrosis or the nephrotic phase of nephritis.
Precautions:
1. Hypercalcemia may develop both spontaneously and as a result of hormonal therapy in women with disseminated breast carcinoma. If it develops while on this agent, the drug should be stopped.
2. Caution is required in administering these agents to patients with cardiac, renal or hepatic disease. Edema may occur occasionally. Concomitant administration with adrenal steroids or ACTH may add to the edema.
3. If amenorrhea or menstrual irregularities develop the drug should be discontinued until the etiology is determined.
4. Anabolic steroids may increase sensitivity to oral anticoagulants. Dosage of the anticoagulant may have to be decreased in order to maintain the prothrombin time at the desired therapeutic level.
5. Anabolic steroids have been shown to alter glucose tolerance tests. Diabetics should be followed carefully and the insulin or oral hypoglycemic dosage adjusted accordingly.
6. Anabolic steroids should be used with caution in patients with benign prostatic hypertrophy.
7. Serum cholesterol may increase during therapy. Therefore, caution is required in administering these agents to patients with a history of myocardial infarction or coronary artery disease. Serial determinations of serum cholesterol should be made and therapy adjusted accordingly, Adverse Reactions:
1. In Males
a. Prepubertal
1) Phallic enlargement
2) Increased frequency of erections b. Post-pubertal
1) Inhibition of testicular function and oligospermia
2) Gynecomastia
2. In Females
a. Hirsutism, male pattern baldness, deepening of the voice and clitoral enlargement. These changes are usually irreversible even after prompt discontinuance of therapy and are not prevented by concomitant use of estrogens.
b. Menstrual irregularities
c. Masculinization of the fetus.
3. In Both Sexes
a. Nausea
b. Increased or decreased libido
c. Acne (especially in females and prepubertal males)
d. Inhibition of gonadotropin secretion.
e. Bleeding in patients on concomitant anticoagulant therapy.
f. Premature closure of epiphysis in children.
4. Alterations in these clinical laboratory tests:
a. The metyrapone test.
b. Glucose tolerance test.
c. The thyroid function tests: a decrease in the FBI, in thyroxine-binding capacity and radioactive iodine uptake.
d. The electrolytes: retention of sodium,
chlorides, water, potassium, phosphates and calcium.
e. Liver function tests:
1) Increased serum cholesterol.
2) Suppression of clotting factors II, V, I, VII, AND X.
Dosage and Administration; Deca-Durablin (nandrolone decanoate injection N.F.) is intended for deep intramuscular injection into the gluteal muscle preferably. For general anabolic effects in adults, the average dosage recommended is 50 to 100 mg. every 3 to 4 weeks. For children from two to thirteen years of age, the average dose is 25 to 50 mg. every; three to four weeks. Higher doses may be required for the treatment of severe disease states such as meta-static breast cancer, refractory anemias, etc,
The recommended dose: 100 to 200 mg, weekly based on therapeutic response, and; consideration of the benefit-to-risk ratio. Duration of therapy will depend on the response of the condition and the appearance of adverse reactions. If possible, therapy should be intermittent.
Supplied: Deca-Durabolin (in sterile sesame oil solution for intramuscular injection) is available in a potency ef 50 mg./cc. with 10% benzyl alcohol (preservative):
1 cc. ampuls, box of 4.
2 cc. multiple dose vial.
Also available in a potency of 100 mg./cc 10% benzyl alcohol (preservative): 2 cc. multiple dose vial.
Caution: Federal law prohibits dispensing without prescription.

Warning: Anabolic steroids do not enhance athletic ability.

This last warning, which has appeared in the PDR, unchanged, for decades, is a testament to what doctors and DEA officials fear: That you'll find out that Deca is a great AS, and that anabolic steroids in general, are highly effective in building muscle and enhancing athletic performance.

Deca is a drug that just about everyone who's taken AS has used at some point. In fact, it is rarely NOT in a cycle these days. It's still cost-effective, it works, and it has a definite place in the scheme of chemicals being dropped in and out of any cycle. But what's new with Deca these days?

What's New?
Does an established steroid change? Do manufacturers make it better along the way? Do they pull it from the market? Mark down its price? Control its availability? Take it off the market when it's arguably the most effective 'roid out there, and the most widely used?

ODDS AND ENDS FACTS ABOUT DECA
~Nandrolone Decanoate is the most counterfeited drug on the black market. It comes in 50, 100, and 200 mg/ cc strength, and is the best injectable for the cost. Typical dose of average bodybuilder? 200 mg/ week for 4-5months!
~It has the most positive results for the fewest side effects - that's including Anavar and Winstrol-V!
~Deca has stubborn metabolites that make it difficult to shake. In the world of drug testing, it's like gum on your proverbial shoe. It has been known to show up as long as 12 month after use in a drug test - Oops!
~Deca is a great choice for women - along with D-bol, Anavar, Winstrol-V, Masteron, and Primobolan Depot
~Testing labs have not usually reported fewer than two parts of nandrolone per billion, in the urine tests of atheltes, but have frequently found cases of competitors with slightly higher readings. It is highly possible that the presence of small traces of the hormone is endogenous in some athletes. But, a more frequent explanation may be the use of food supplements that contain 19-norandrosterone, the precursor of nandrolone. Since 19-Nor has now been upgraded to illegal status, it's likely that this "higher reading" will be found unless it's a legitimate "dirty test".
~ Steroids enhance erythropoiesis, and Deca is a particularly good enhancers of increasing red blood cell production (to appear that you have blood doped). Six Olympians were flagged for this in the drug testing phase in Torino - the outcome has yet to be determined since change in altitude and dehydration can also lend this appearance.
~ Did you know that Deca and Winstrol-V is the most common stack of AS?
~ Did you know the most common stack for bulking is Deca and D-Bol? And did you also know that if you don't eat like a pig, you could also use this very stack to cut up if you weren't able to get your hands on anything else? We've seen some miraculous results on both if steak and vegetables is the mainstay of your diet.
~ Did you know that Deca gives less side effect activity in the scalp, skin and prostate?
~ Did you know that Deca actually binds better than testosterone at the androgen receptor in the muscle tissue? Yet, sadly, it gives only about half the muscle-building results per milligram.
~ Did you know that using Deca alone, without any other AAS may result in complete inability to perform sexually?
~ Did you know that Deca is made in a complex chemical process, sometimes using part of the Mexican Agare plant?
~ Did you know that Deca is injected into women to treat breast cancer, and men and women to treat some blood disorders (because of its erythropoietic activity) and to rebuild muscles after debilitating diseases?
~ When faced with an alleged false positive result, Lenny Paul, the British bobsledder, claimed his positive result was the result of eating Spaghetti Bolognese, and Germany's Deiter Baumann claimed his toothpaste had been spiked?
~ Did you know that the Brits and Aussies often blame "wild boar offal" for a positive Nandrolone test result? (Offal is a combination of any of the throw away organs from meat: heart, lungs, etc...)
Dane Fletcher is THE Training Authority and writes exclusively for GetAnabolics.com, a leading provider of <a href=”http://www.getanabolics.com/fat-burners-c-35.html” title=”Fat Loss Supplements”>Fat Loss Supplements</a> and safe, legal <a href=”” title=”Testosterone”>Testosterone</a> Boosters. For more information, please visit <a href=”http://www.getanabolics.com” title=”GetAnabolics.com”>http://www.getanabolics.com</a>

Article Source: http://www.lifeweightloss.com

Dane Fletcher is THE Training Authority and writes exclusively for GetAnabolics.com, a leading provider of Bodybuilding Supplements and alternatives to Steroids. For more information, please www.getanabolics.com.

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